Gerd Heusch,H. Grobecker,B.E. Strauer's Angiotensin and the Heart PDF

By Gerd Heusch,H. Grobecker,B.E. Strauer

ISBN-10: 0387914323

ISBN-13: 9780387914329

ISBN-10: 3798509360

ISBN-13: 9783798509368

within the final decade, ACE inhibitors became a cornerstone of cardiovascular drug remedy. priceless results in sufferers with high blood pressure, middle failure, and submit myocardial infarction were validated in huge scientific trials. In parallel, ex perimental learn has shifted the curiosity from the speedy homeostatic functionality of the circulating renin-angiotensin-system to the a number of paracrine features of neighborhood tissue renin-angiotensin-systems, together with hypertrophy, hyperplasia, athe- oenesis, and vasomotion. . It used to be the purpose or a symposium held in Hamburg, October 22-24, 1992, to collect a global panel of experimental and medical scientists and to debate the latest findings at the position of angiotensin and linked mediators in motor vehicle diovascular version and disorder, with a specific emphasis at the remedy of such ailment by means of ACE inhibitors. The assembly and this book have been generously supported through Astra chemical substances. H. Grobecker G. Heusch B. E. Strauer Contents Foreword. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V advent neighborhood expression and pathophysiological position of renin-angiotensin within the blood vessels and center Dzau, V. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Myocardial Perfusion Angiotensin, ACE-inhibitors and endothelial keep watch over of vasomotor tone Luscher, T. F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 neighborhood and neurohumoral keep watch over of coronary blood move Krajcar, M., G. Heusch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 ACE-inhibitors in coronary artery disorder? Vogt, M., W. Matz, B. E. Strauer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . forty three Myocardial Hypertrophy Molecular mechanisms of cardiac gene expression Nadal-Ginard, B., V. Mahdavi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . sixty five Myocardial perfusion based and autonomous mechanisms of nearby myocardial disorder in hypertrophy Vatner, S. F., L. Hittinger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Angiotensin and the Heart by Gerd Heusch,H. Grobecker,B.E. Strauer


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